Publications 2007
Aguet Michel
van Bezooijen, R. L., Deruiter, M. C., Vilain, N., Monteiro, R. M., Visser, A., van der Wee-Pals, L., van Munsteren, C. J., Hogendoorn, P. C., Aguet, M., Mummery, C. L., Papapoulos, S. E., Ten Dijke, P., and Lowik, C. W. (2007). SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development. Dev Dyn 236, 606-612. Abstract

Wilson, A., Ardiet, D. L., Saner, C., Vilain, N., Beermann, F., Aguet, M., Macdonald, H. R., and Zilian, O. (2007). Normal hemopoiesis and lymphopoiesis in the combined absence of numb and numblike. J Immunol 178, 6746-6751. Abstract
Beard Peter
Garner, E., Martinon, F., Tschopp, J., Beard, P., and Raj, K. (2007). Cells with Defective p53-p21-pRb Pathway Are Susceptible to Apoptosis Induced by p84N5 via Caspase-6. Cancer Res 67, 7631-7637. Abstract

Jurvansuu, J., Fragkos, M., Ingemarsdotter, C., and Beard, P. (2007). Chk1 Instability Is Coupled to Mitotic Cell Death of p53-deficient Cells in Response to Virus-induced DNA Damage Signaling. J Mol Biol 372, 397-406. Abstract
Beermann Friedrich
Delmas, V., Beermann, F., Martinozzi, S., Carreira, S., Ackermann, J., Kumasaka, M., Denat, L., Goodall, J., Luciani, F., Viros, A., Demirkan, N., Bastian, B. C., Goding, C. R., and Larue, L. (2007). beta-Catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development. Genes Dev 21, 2923-2935. Abstract

Frau, E., Magnon, C., Opolon, P., Connault, E., Opolon, D., Beermann, F., Abitbol, M., Perricaudet, M., and Bouquet, C. (2007). A gene transfer comparative study of HSA-conjugated antiangiogenic factors in a transgenic mouse model of metastatic ocular cancer. Cancer Gene Ther 14, 440. Abstract

Johansson, K. A., Dursun, U., Jordan, N., Gu, G., Beermann, F., Gradwohl, G., and Grapin-Botton, A. (2007). Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev Cell 12, 457-465. Abstract

Kianizad, K., Marshall, L. A., Grinshtein, N., Bernard, D., Margl, R., Cheng, S., Beermann, F., Wan, Y., and Bramson, J. (2007). Elevated frequencies of self-reactive CD8+ T cells following immunization with a xenoantigen are due to the presence of a heteroclitic CD4+ T-cell helper epitope. Cancer Res 67, 6459-6467. Abstract

Larue, L., and Beermann, F. (2007). Cutaneous melanoma in genetically modified animals. Pigment Cell Res 20, 485-497. Abstract

Murisier, F., Guichard, S., and Beermann, F. (2007). Distinct distal regulatory elements control tyrosinase expression in melanocytes and the retinal pigment epithelium. Dev Biol 303, 838-847. Abstract

Murisier, F., Guichard, S., and Beermann, F. (2007). The tyrosinase enhancer is activated by Sox10 and Mitf in mouse melanocytes. Pigment Cell Res 20, 173-184. Abstract

Schouwey, K., Delmas, V., Larue, L., Zimber-Strobl, U., Strobl, L. J., Radtke, F., and Beermann, F. (2007). Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner. Dev Dyn 236, 282-289. Abstract

Stecca, B., Mas, C., Clement, V., Zbinden, M., Correa, R., Piguet, V., Beermann, F., and Ruiz, I. A. A. (2007). Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways. Proc Natl Acad Sci U S A 104, 5895-5900. Abstract

Steiner, Q. G., Otten, L. A., Hicks, M. J., Kaya, G., Grosjean, F., Saeuberli, E., Lavanchy, C., Beermann, F., McClain, K. L., and Acha-Orbea, H. (2007). In vivo transformation of mouse conventional CD8{alpha}+ dendritic cells leads to progressive multisystem histiocytosis. Blood in press. Abstract

Wilson, A., Ardiet, D. L., Saner, C., Vilain, N., Beermann, F., Aguet, M., Macdonald, H. R., and Zilian, O. (2007). Normal hemopoiesis and lymphopoiesis in the combined absence of numb and numblike. J Immunol 178, 6746-6751. Abstract

Wiznerowicz, M., Jakobsson, J., Szulc, J., Liao, S., Quazzola, A., Beermann, F., Aebischer, P., and Trono, D. (2007). The Kruppel-associated Box Repressor Domain Can Trigger de Novo Promoter Methylation during Mouse Early Embryogenesis. J Biol Chem 282, 34535-34541. Abstract
Brisken Cathrin
Brisken, C., and Duss, S. (2007). Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective. Stem Cell Rev 3, 147-156. Abstract

Ciarloni, L., Mallepell, S., and Brisken, C. (2007). Amphiregulin is an essential mediator of estrogen receptor {alpha} function in mammary gland development. Proc Natl Acad Sci U S A 104, 5455-5460. Abstract

Duss, S., Andre, S., Nicoulaz, A. L., Fiche, M., Bonnefoi, H., Brisken, C., and Iggo, R. D. (2007). An estrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells. Breast Cancer Res 9, R38. Abstract
Bucher Philipp
Girod, P. A., Nguyen, D. Q., Calabrese, D., Puttini, S., Grandjean, M., Martinet, D., Regamey, A., Saugy, D., Beckmann, J. S., Bucher, P., and Mermod, N. (2007). Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells. Nat Methods 4, 747-753. Abstract

Iseli, C., Ambrosini, G., Bucher, P., and Jongeneel, C. V. (2007). Indexing strategies for rapid searches of short words in genome sequences. PLoS ONE 2, e579. Abstract

Rambaldi, D., Felice, B., Praz, V., Bucher, P., Cittaro, D., and Guffanti, A. (2007). Splicy: a web-based tool for the prediction of possible alternative splicing events from Affymetrix probeset data. BMC Bioinformatics 8 Suppl 1, S17. Abstract

Retelska, D., Beaudoing, E., Notredame, C., Jongeneel, C. V., and Bucher, P. (2007). Vertebrate conserved non coding DNA regions have a high persistence length and a short persistence time. BMC Genomics 8, 398. Abstract

Schmid, C., and Bucher, P. (2007). ChIP-Seq Data Reveal Nucleosome Architecture of Human Promoters. Cell 131, 1-2.

Schmid, C. D., Sengstag, T., Bucher, P., and Delorenzi, M. (2007). MADAP, a flexible clustering tool for the interpretation of one-dimensional genome annotation data. Nucleic Acids Res 35, W201-205. Abstract
Constam Daniel
Grapin-Botton, A., and Constam, D. (2007). Evolution of the mechanisms and molecular control of endoderm formation. Mech Dev 124, 253-278. Abstract
Delorenzi Mauro
Bonnefoi, H., Potti, A., Delorenzi, M., Mauriac, L., Campone, M., Tubiana-Hulin, M., Petit, T., Rouanet, P., Jassem, J., Blot, E., Becette, V., Farmer, P., Andre, S., Acharya, C. R., Mukherjee, S., Cameron, D., Bergh, J., Nevins, J. R., and Iggo, R. D. (2007). Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: a substudy of the EORTC 10994/BIG 00-01 clinical trial. Lancet Oncol in press. Abstract

Desmedt, C., Piette, F., Loi, S., Wang, Y., Lallemand, F., Haibe-Kains, B., Viale, G., Delorenzi, M., Zhang, Y., d'Assignies, M. S., Bergh, J., Lidereau, R., Ellis, P., Harris, A. L., Klijn, J. G., Foekens, J. A., Cardoso, F., Piccart, M. J., Buyse, M., and Sotiriou, C. (2007). Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series. Clin Cancer Res 13, 3207-3214. Abstract

Goldstein, D. R., Delorenzi, M., Luthy-Carter, R., and Sengstag, T. (2007). Statistical design and data analysis for microarray experiments. In Meta-Analysis and Combining Information in Genetics, R. Guerra, and D. Allison, eds. (Chapman and Hall). in press

Guipponi, M., Toh, M. Y., Tan, J., Park, D., Hanson, K., Ballana, E., Kwong, D., Cannon, P. Z., Wu, Q., Gout, A., Delorenzi, M., Speed, T. P., Smith, R. J., Dahl, H. H., Petersen, M., Teasdale, R. D., Estivill, X., Park, W. J., and Scott, H. S. (2007). An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss. Hum Mutat in press. Abstract

Kuhn, A., Goldstein, D. R., Hodges, A., Strand, A. D., Sengstag, T., Kooperberg, C., Becanovic, K., Pouladi, M. A., Sathasivam, K., Cha, J. H., Hannan, A. J., Hayden, M. R., Leavitt, B. R., Dunnett, S. B., Ferrante, R. J., Albin, R., Shelbourne, P., Delorenzi, M., Augood, S. J., Faull, R. L., Olson, J. M., Bates, G. P., Jones, L., and Luthi-Carter, R. (2007). Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage. Hum Mol Genet 16, 1845-1861. Abstract

Loi, S., Haibe-Kains, B., Desmedt, C., Lallemand, F., Tutt, A. M., Gillet, C., Ellis, P., Harris, A., Bergh, J., Foekens, J. A., Klijn, J. G., Larsimont, D., Buyse, M., Bontempi, G., Delorenzi, M., Piccart, M. J., and Sotiriou, C. (2007). Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade. J Clin Oncol 25, 1239-1246. Abstract

Prandini, P., Deutsch, S., Lyle, R., Gagnebin, M., Delucinge Vivier, C., Delorenzi, M., Gehrig, C., Descombes, P., Sherman, S., Dagna Bricarelli, F., Baldo, C., Novelli, A., Dallapiccola, B., and Antonarakis, S. E. (2007). Natural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalance. Am J Hum Genet 81, 252-263. Abstract

Runne, H., Kuhn, A., Wild, E. J., Pratyaksha, W., Kristiansen, M., Isaacs, J. D., Regulier, E., Delorenzi, M., Tabrizi, S. J., and Luthi-Carter, R. (2007). Analysis of potential transcriptomic biomarkers for Huntington's disease in peripheral blood. Proc Natl Acad Sci U S A 104, 14424-14429. Abstract

Schmid, C. D., Sengstag, T., Bucher, P., and Delorenzi, M. (2007). MADAP, a flexible clustering tool for the interpretation of one-dimensional genome annotation data. Nucleic Acids Res 35, W201-205. Abstract

Vuaroqueaux, V., Urban, P., Labuhn, M., Delorenzi, M., Wirapati, P., Benz, C. C., Flury, R., Dieterich, H., Spyratos, F., Eppenberger, U., and Eppenberger-Castori, S. (2007). Low E2F1 transcript levels are a strong determinant of favorable breast cancer outcome. Breast Cancer Res 9, R33. Abstract
Gönczy Pierre
Bellanger, J. M., Carter, J. C., Phillips, J. B., Canard, C., Bowerman, B., and Gönczy, P. (2007). ZYG-9, TAC-1 and ZYG-8 together ensure correct microtubule function throughout the cell cycle of C. elegans embryos. J Cell Sci 120, 2963-2973. Abstract

Hachet, V., Canard, C., and Gönczy, P. (2007). Centrosomes Promote Timely Mitotic Entry in C. elegans Embryos. Dev Cell 12, 531-541. Abstract

Nguyen-Ngoc, T., Afshar, K., and Gönczy, P. (2007). Coupling of cortical dynein and Galpha proteins mediates spindle positioning in Caenorhabditis elegans. Nat Cell Biol 9, 1294-1302. Abstract

Strnad, P., Leidel, S., Vinogradova, T., Euteneuer, U., Khodjakov, A., and Gönczy, P. (2007). Regulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycle. Dev Cell 13, 203-213. Abstract
Grapin-Botton Anne
Grapin-Botton, A., and Constam, D. (2007). Evolution of the mechanisms and molecular control of endoderm formation. Mech Dev 124, 253-278. Abstract

Grapin-Botton, A., Heimberg, H., and Lemaigre, F. (2007). The genetic programme of pancreatic beta-cells: basic science for the development of beta-cell therapy. Workshop on programming pancreatic beta-cells. EMBO Rep 8, 322-326. Abstract

Johansson, K. A., Dursun, U., Jordan, N., Gu, G., Beermann, F., Gradwohl, G., and Grapin-Botton, A. (2007). Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev Cell 12, 457-465. Abstract
Huelsken Joerg
Baurand, A., Zelarayan, L., Betney, R., Gehrke, C., Dunger, S., Noack, C., Busjahn, A., Huelsken, J., Taketo, M. M., Birchmeier, W., Dietz, R., and Bergmann, M. W. (2007). Beta-catenin downregulation is required for adaptive cardiac remodeling. Circ Res 100, 1353-1362. Abstract

Faraldo, M. M., Teuliere, J., Deugnier, M. A., Birchmeier, W., Huelsken, J., Thiery, J. P., Cano, A., and Glukhova, M. A. (2007). beta-Catenin regulates P-cadherin expression in mammary basal epithelial cells. FEBS Lett 581, 831-836. Abstract

Fevr, T., Robine, S., Louvard, D., and Huelsken, J. (2007). Wnt/{beta}-Catenin Is Essential for Intestinal Homeostasis and Maintenance of Intestinal Stem Cells. Mol Cell Biol 27, 7551-7559. Abstract

Jeannet, G., Scheller, M., Scarpellino, L., Duboux, S., Gardiol, N., Back, J., Kuttler, F., Malanchi, I., Birchmeier, W., Leutz, A., Huelsken, J., and Held, W. (2007). Long-term, multilineage hematopoiesis occurs in the combined absence of {beta}-catenin and {gamma}-catenin. Blood in press. Abstract

Schaeper, U., Vogel, R., Chmielowiec, J., Huelsken, J., Rosario, M., and Birchmeier, W. (2007). Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo. Proc Natl Acad Sci U S A 104, 15376-15381. Abstract
Lingner Joachim
Arneric, M., and Lingner, J. (2007). Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast. EMBO Rep 8, 1080-1085. Abstract

Azzalin, C. M., and Lingner, J. (2007). Molecular biology: damage control. Nature 448, 1001-1002. Abstract

Azzalin, C. M., Reichenbach, P., Khoriauli, L., Giulotto, E., and Lingner, J. (2007). Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science 318, 798-801. Abstract

Chang, M., Arneric, M., and Lingner, J. (2007). Telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae. Genes Dev 21, 2485-2494. Abstract

Cristofari, G., Adolf, E., Reichenbach, P., Sikora, K., Terns, R. M., Terns, M. P., and Lingner, J. (2007). Human telomerase RNA accumulation in cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation. Mol Cell 27, 882-889. Abstract

Cristofari, G., Reichenbach, P., Regamey, P. O., Banfi, D., Chambon, M., Turcatti, G., and Lingner, J. (2007). Low- to high-throughput analysis of telomerase modulators with Telospot. Nat Methods 4, 851-853. Abstract

Cristofari, G., Sikora, K., and Lingner, J. (2007). Telomerase unplugged. ACS Chem Biol 2, 155-158. Abstract

De Cian, A., Cristofari, G., Reichenbach, P., De Lemos, E., Monchaud, D., Teulade-Fichou, M. P., Shin-Ya, K., Lacroix, L., Lingner, J., and Mergny, J. L. (2007). Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action. Proc Natl Acad Sci U.S.A 104, 17347-17352. Abstract

Luke, B., Azzalin, C. M., Hug, N., Deplazes, A., Peter, M., and Lingner, J. (2007). Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay. Nucleic Acids Res in press. Abstract

Redon, S., Reichenbach, P., and Lingner, J. (2007). Protein-RNA and protein-protein interactions mediate association of human EST1A/SMG6 with telomerase. Nucleic Acids Res in press.
Naef Félix
Boothroyd, C. E., Wijnen, H., Naef, F., Saez, L., and Young, M. W. (2007). Integration of Light and Temperature in the Regulation of Circadian Gene Expression in Drosophila. PLoS Genet 3, e54. Abstract

Parisi, F., Wirapati, P., and Naef, F. (2007). Identifying synergistic regulation involving c-Myc and sp1 in human tissues. Nucleic Acids Res 35, 1098-1107. Abstract

Rougemont, J., and Naef, F. (2007). Dynamical signatures of cellular fluctuations and oscillator stability in peripheral circadian clocks. Mol Syst Biol 3, Article 93. Abstract

Stoll, G., Rougemont, J., and Naef, F. (2007). Representing perturbed dynamics in biological network models. Phys Rev E Stat Nonlin Soft Matter Phys 76, 011917. Abstract
Radtke Freddy
Amsen, D., Antov, A., Jankovic, D., Sher, A., Radtke, F., Souabni, A., Busslinger, M., McCright, B., Gridley, T., and Flavell, R. A. (2007). Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 27, 89-99. Abstract

Besseyrias, V., Fiorini, E., Strobl, L. J., Zimber-Strobl, U., Dumortier, A., Koch, U., Arcangeli, M. L., Ezine, S., Macdonald, H. R., and Radtke, F. (2007). Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation. J Exp Med 204, 331-343. Abstract

Kelly, A. P., Finlay, D. K., Hinton, H. J., Clarke, R. G., Fiorini, E., Radtke, F., and Cantrell, D. A. (2007). Notch-induced T cell development requires phosphoinositide-dependent kinase 1. Embo J 26, 3441-3450. Abstract

Koch, U., and Radtke, F. (2007). Haematopoietic stem cell niche in Drosophila. Bioessays 29, 713-716. Abstract

Koch, U., and Radtke, F. (2007). Notch and cancer: a double-edged sword. Cell Mol Life Sci in press. Abstract

Koch, U., Wilson, A., Cobas, M., Kemler, R., Macdonald, H. R., and Radtke, F. (2007). Simultaneous loss of {beta}- and {gamma}-catenin does not perturb hematopoiesis or lymphopoiesis. Blood in press. Abstract

Komine, O., Nagaoka, M., Watase, K., Gutmann, D. H., Tanigaki, K., Honjo, T., Radtke, F., Saito, T., Chiba, S., and Tanaka, K. (2007). The monolayer formation of Bergmann glial cells is regulated by Notch/RBP-J signaling. Dev Biol 311, 238-250. Abstract

Santos, M. A., Sarmento, L. M., Rebelo, M., Doce, A. A., Maillard, I., Dumortier, A., Neves, H., Radtke, F., Pear, W. S., Parreira, L., and Demengeot, J. (2007). Notch1 engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells. Proc Natl Acad Sci U S A 104, 15454-15459. Abstract

Schouwey, K., Delmas, V., Larue, L., Zimber-Strobl, U., Strobl, L. J., Radtke, F., and Beermann, F. (2007). Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner. Dev Dyn 236, 282-289. Abstract

Takeshita, K., Satoh, M., Ii, M., Silver, M., Limbourg, F. P., Mukai, Y., Rikitake, Y., Radtke, F., Gridley, T., Losordo, D. W., and Liao, J. K. (2007). Critical role of endothelial Notch1 signaling in postnatal angiogenesis. Circ Res 100, 70-78. Abstract

Vauclair, S., Majo, F., Durham, A. D., Ghyselinck, N. B., Barrandon, Y., and Radtke, F. (2007). Corneal epithelial cell fate is maintained during repair by Notch1 signaling via the regulation of vitamin A metabolism. Dev Cell 13, 242-253. Abstract
Rufer Nathalie
Appay, V., Bosio, A., Lokan, S., Wiencek, Y., Biervert, C., Kusters, D., Devevre, E., Speiser, D., Romero, P., Rufer, N., and Leyvraz, S. (2007). Sensitive Gene Expression Profiling of Human T Cell Subsets Reveals Parallel Post-Thymic Differentiation for CD4+ and CD8+ Lineages. J Immunol 179, 7406-7414. Abstract

Appay, V., Voelter, V., Rufer, N., Reynard, S., Jandus, C., Gasparini, D., Lienard, D., Speiser, D. E., Schneider, P., Cerottini, J. C., Romero, P., and Leyvraz, S. (2007). Combination of transient lymphodepletion with busulfan and fludarabine and peptide vaccination in a phase I clinical trial for patients with advanced melanoma. J Immunother 30, 240-250. Abstract

Barbey, C., Baumgaertner, P., Devevre, E., Rubio-Godoy, V., Derre, L., Bricard, G., Guillaume, P., Luescher, I. F., Lienard, D., Cerottini, J. C., Romero, P., Rufer, N., and Speiser, D. E. (2007). IL-12 Controls Cytotoxicity of a Novel Subset of Self-Antigen-Specific Human CD28+ Cytolytic T Cells. J Immunol 178, 3566-3574. Abstract

Derre, L., Bruyninx, M., Baumgaertner, P., Devevre, E., Corthesy, P., Touvrey, C., Mahnke, Y. D., Pircher, H., Voelter, V., Romero, P., Speiser, D. E., and Rufer, N. (2007). In Vivo Persistence of Codominant Human CD8+ T Cell Clonotypes Is Not Limited by Replicative Senescence or Functional Alteration. J Immunol 179, 2368-2379. Abstract

Jorritsma, A., Gomez-Eerland, R., Dokter, M., van de Kasteele, W., Zoet, Y. M., Doxiadis, II, Rufer, N., Romero, P., Morgan, R. A., Schumacher, T. N., and Haanen, J. B. (2007). Selecting highly affine and well-expressed TCRs for gene therapy of melanoma. Blood 110, 3564-3572. Abstract

Romero, P., Zippelius, A., Kurth, I., Pittet, M. J., Touvrey, C., Iancu, E. M., Corthesy, P., Devevre, E., Speiser, D. E., and Rufer, N. (2007). Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes. J Immunol 178, 4112-4119. Abstract
Simanis Viesturs
Presti, L. L., Cockell, M., Cerutti, L., Simanis, V., and Hauser, P. M. (2007). Functional characterization of Pneumocystis carinii brl1 by trans-species complementation analysis. Eukaryot Cell in press. Abstract
Trumpp Andreas
Ju, Z., Jiang, H., Jaworski, M., Rathinam, C., Gompf, A., Klein, C., Trumpp, A., and Rudolph, K. L. (2007). Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment. Nat Med 13, 742-747. Abstract

Strom, A., Bonal, C., Ashery-Padan, R., Hashimoto, N., Campos, M. L., Trumpp, A., Noda, T., Kido, Y., Real, F. X., Thorel, F., and Herrera, P. L. (2007). Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas. Development 134, 2719-2725. Abstract

Trumpp, A. (2007). c-Myc and activated Ras during skin tumorigenesis: cooperation at the cancer stem cell level? In: Cancer stem cells: novel concepts and prospects for tumor therapy, O. A. Wiestler, B. Haendler and D. Mumberg, eds. (Berlin Heidelberg, Springer), pp. 13-26.

Wilson, A., Oser, G. M., Jaworski, M., Blanco-Bose, W. E., Laurenti, E., Adolphe, C., Essers, M. A., Macdonald, H. R., and Trumpp, A. (2007). Dormant and self-renewing hematopoietic stem cells and their niches. Ann N Y Acad Sci 1106, 64-75. Abstract