Delorenzi Mauro  
Bonnefoi, H., Potti, A., Delorenzi, M., Mauriac, L., Campone, M., Tubiana-Hulin, M., Petit, T., Rouanet, P., Jassem, J., Blot, E., Becette, V., Farmer, P., Andre, S., Acharya, C. R., Mukherjee, S., Cameron, D., Bergh, J., Nevins, J. R., and Iggo, R. D. (2007). Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: a substudy of the EORTC 10994/BIG 00-01 clinical trial. Lancet Oncol in press. Abstract

Desmedt, C., Piette, F., Loi, S., Wang, Y., Lallemand, F., Haibe-Kains, B., Viale, G., Delorenzi, M., Zhang, Y., d'Assignies, M. S., Bergh, J., Lidereau, R., Ellis, P., Harris, A. L., Klijn, J. G., Foekens, J. A., Cardoso, F., Piccart, M. J., Buyse, M., and Sotiriou, C. (2007). Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series. Clin Cancer Res 13, 3207-3214. Abstract

Goldstein, D. R., Delorenzi, M., Luthy-Carter, R., and Sengstag, T. (2007). Statistical design and data analysis for microarray experiments. In Meta-Analysis and Combining Information in Genetics, R. Guerra, and D. Allison, eds. (Chapman and Hall). in press

Guipponi, M., Toh, M. Y., Tan, J., Park, D., Hanson, K., Ballana, E., Kwong, D., Cannon, P. Z., Wu, Q., Gout, A., Delorenzi, M., Speed, T. P., Smith, R. J., Dahl, H. H., Petersen, M., Teasdale, R. D., Estivill, X., Park, W. J., and Scott, H. S. (2007). An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss. Hum Mutat in press. Abstract

Kuhn, A., Goldstein, D. R., Hodges, A., Strand, A. D., Sengstag, T., Kooperberg, C., Becanovic, K., Pouladi, M. A., Sathasivam, K., Cha, J. H., Hannan, A. J., Hayden, M. R., Leavitt, B. R., Dunnett, S. B., Ferrante, R. J., Albin, R., Shelbourne, P., Delorenzi, M., Augood, S. J., Faull, R. L., Olson, J. M., Bates, G. P., Jones, L., and Luthi-Carter, R. (2007). Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage. Hum Mol Genet 16, 1845-1861. Abstract

Loi, S., Haibe-Kains, B., Desmedt, C., Lallemand, F., Tutt, A. M., Gillet, C., Ellis, P., Harris, A., Bergh, J., Foekens, J. A., Klijn, J. G., Larsimont, D., Buyse, M., Bontempi, G., Delorenzi, M., Piccart, M. J., and Sotiriou, C. (2007). Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade. J Clin Oncol 25, 1239-1246. Abstract

Prandini, P., Deutsch, S., Lyle, R., Gagnebin, M., Delucinge Vivier, C., Delorenzi, M., Gehrig, C., Descombes, P., Sherman, S., Dagna Bricarelli, F., Baldo, C., Novelli, A., Dallapiccola, B., and Antonarakis, S. E. (2007). Natural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalance. Am J Hum Genet 81, 252-263. Abstract

Runne, H., Kuhn, A., Wild, E. J., Pratyaksha, W., Kristiansen, M., Isaacs, J. D., Regulier, E., Delorenzi, M., Tabrizi, S. J., and Luthi-Carter, R. (2007). Analysis of potential transcriptomic biomarkers for Huntington's disease in peripheral blood. Proc Natl Acad Sci U S A 104, 14424-14429. Abstract

Schmid, C. D., Sengstag, T., Bucher, P., and Delorenzi, M. (2007). MADAP, a flexible clustering tool for the interpretation of one-dimensional genome annotation data. Nucleic Acids Res 35, W201-205. Abstract

Vuaroqueaux, V., Urban, P., Labuhn, M., Delorenzi, M., Wirapati, P., Benz, C. C., Flury, R., Dieterich, H., Spyratos, F., Eppenberger, U., and Eppenberger-Castori, S. (2007). Low E2F1 transcript levels are a strong determinant of favorable breast cancer outcome. Breast Cancer Res 9, R33. Abstract
Bacac, M, Migliavacca, E, Stehle, JC, McKee, T, Delorenzi, M, Coindre, JM, Guillou, L, and Stamenkovic, I (2006). A gene expression signature that distinguishes desmoid tumours from nodular fasciitis. J Pathol. 208,543-53. Abstract

Buyse, M., Loi, S., van't Veer, L., Viale, G., Delorenzi, M., Glas, A. M., d'Assignies, M. S., Bergh, J., Lidereau, R., Ellis, P., Harris, A., Bogaerts, J., Therasse, P., Floore, A., Amakrane, M., Piette, F., Rutgers, E., Sotiriou, C., Cardoso, F., and Piccart, M. J. (2006). Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer. J Natl Cancer Inst 98, 1183-1192. Abstract

Gotthardt, D., Blancheteau, V., Bosserhoff, A., Ruppert, T., Delorenzi, M., and Soldati, T. (2006). Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake. Mol Cell Proteomics 5, 2228-2243. Abstract

Hodges, A., Strand, A. D., Aragaki, A. K., Kuhn, A., Sengstag, T., Hughes, G., Elliston, L. A., Hartog, C., Goldstein, D. R., Thu, D., Hollingsworth, Z. R., Collin, F., Synek, B., Holmans, P. A., Young, A. B., Wexler, N. S., Delorenzi, M., Kooperberg, C., Augood, S. J., Faull, R. L., Olson, J. M., Jones, L. , and  Luthi-Carter, R. (2006). Regional and cellular gene expression changes in human Huntington's disease brain. Hum Mol Genet 15, 965-977. Abstract

Jagannathan, V, Roulet, E, Delorenzi, M, and Bucher, P (2006). HTPSELEX--a database of high-throughput SELEX libraries for transcription factor binding sites. Nucleic Acids Res 34, D90-94. Abstract

Leupin, N., Kuhn, A., Hugli, B., Grob, T. J., Jaggi, R., Tobler, A., Delorenzi, M., and Fey, M. F. (2006). Gene expression profiling reveals consistent differences between clinical samples of human leukaemias and their model cell lines. Br J Haematol 135, 520-523. Abstract

Menzel, O., Migliaccio, M., Goldstein, D. R., Dahoun, S., Delorenzi, M., and Rufer, N. (2006). Mechanisms regulating the proliferative potential of human CD8+ T lymphocytes overexpressing telomerase. J Immunol 177, 3657-3668. Abstract

Sotiriou, C., Wirapati, P., Loi, S., Harris, A., Fox, S., Smeds, J., Nordgren, H., Farmer, P., Praz, V., Haibe-Kains, B., Desmedt, C., Larsimont, D., Cardoso, F., Peterse, H., Nuyten, D., Buyse, M., Van de Vijver, M. J., Bergh, J., Piccart, M. , and Delorenzi, M. (2006). Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis. J Natl Cancer Inst 98, 262-272. Abstract

Urban, P., Vuaroqueaux, V., Labuhn, M., Delorenzi, M., Wirapati, P., Wight, E., Senn, H. J., Benz, C., Eppenberger, U., and Eppenberger-Castori, S. (2006). Increased expression of urokinase-type plasminogen activator mRNA determines adverse prognosis in ErbB2-positive primary breast cancer. J Clin Oncol 24, 4245-4253. Abstract

Anderle, P., Sengstag, T., Mutch, D. M., Rumbo, M., Praz, V., Mansourian, R., Delorenzi, M., Williamson, G. , and Roberts, M. A. (2005). Changes in the transcriptional profile of transporters in the intestine along the anterior-posterior and crypt-villus axes. BMC Genomics 6, 69. Abstract

Beckmann, J. S., Maurer, F., Delorenzi, M. , and Falquet, L. (2005). On ubiquitin ligases and cancer. Hum Mutat 25, 507-512. Abstract

Farmer, P., Bonnefoi, H., Becette, V., Tubiana-Hulin, M., Fumoleau, P., Larsimont, D., Macgrogan, G., Bergh, J., Cameron, D., Goldstein, D., Duss, S., Nicoulaz, A. L., Brisken, C., Fiche, M., Delorenzi, M., and Iggo, R. (2005). Identification of molecular apocrine breast tumours by microarray analysis. Oncogene 24, 4660-4671. Abstract

Jongeneel, C. V., Delorenzi, M., Iseli, C., Zhou, D., Haudenschild, C. D., Khrebtukova, I., Kuznetsov, D., Stevenson, B. J., Strausberg, R. L., Simpson, A. J. , and Vasicek, T. J. (2005). An atlas of human gene expression from massively parallel signature sequencing (MPSS). Genome Res 15, 1007-1014. Abstract
Bourgon, R, Delorenzi, M, Sargeant, T, Hodder, AN, Crabb, BS, and Speed, TP (2004). The Serine repeat antigen (SERA) gene family phylogeny in plasmodium: the impact of GC content and reconciliation of gene and species trees. Mol Biol Evol 21, 2161-2171. Abstract

De Fourmestraux, V, Neubauer, H, Poussin, C, Farmer, P, Falquet, L, Burcelin, R, Delorenzi, M, and Thorens, B (2004). Transcript profiling suggests that differential metabolic adaptation of mice to high fat diet is associated with changes in liver to muscle lipid fluxes. J Biol Chem. 279, 50743-50753. Abstract

Goldstein, D.R. and Delorenzi, M. (2004). Statistical design and data analysis for microarray experiments. In : Unraveling Lipid Metabolism with Microarrays, A. Berger and M.A. Roberts (eds). New York: Dekker.

Schmid, C. D., Praz, V., Delorenzi, M., Perier, R., and Bucher, P. (2004). The Eukaryotic Promoter Database EPD: the impact of in silico primer extension. Nucleic Acids Res 32 Database issue, D82-85. Full text
Godard, S., Getz, G., Delorenzi, M., Farmer, P., Kobayashi, H., Desbaillets, I., Nozaki, M., Diserens, A.C., Hamou, M.F., Dietrich, P.Y., Regli, L., Janzer, R.C., Bucher, P., Stupp, R., de Tribolet, N., Domany, E., Hegi, M.E. (2003). Classification of human astrocytic gliomas on the basis of gene expression: A correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes. Cancer Res 63, 6613-6625. Abstract

Hodder, A.N., Drew, D., Epa, V.C., Delorenzi, M., Bourgon, R., Miller, S.K., Moritz, R.L., Frecklington, D.F., Simpson, R.J., Speed, T.P., Pike, R.N., Crabb, B.S. (2003). Enzymic, phylogenetic and structural characterization of the unusual papain-like protease domain of Plasmodium falciparum SERA5. J Biol Chem 278, 48169-48177. Abstract
Delorenzi M and Speed T (2002). An HMM model for coiled-coil domains and a comparison with PSSM-based predictions. Bioinformatics. 18, 617-625. Abstract

Miller SK, Good RT, Drew DR, Delorenzi M, Sanders PR, Hodder AN, Speed TP, Cowman AF, de Koning-Ward TF, Crabb BS. (2002). A subset of Plasmodium falciparum SERA genes are expressed and appear to play an important role in the erythrocytic cycle. J Biol Chem. 277, 47524-32. Abstract

Delorenzi M, Sexton A, Shams-Eldin H, Schwarz R, Speed T, Schofield L (2002). Genes For Glycosylphosphatidylinositol Toxin Biosynthesis In Plasmodium falciparum. Infect. Immun. 70, 4510-4522. Abstract
 
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