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Arneric, M., and Lingner, J. (2007). Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast. EMBO Rep 8, 1080-1085. Abstract
Azzalin, C. M., and Lingner, J. (2007). Molecular biology: damage control. Nature 448, 1001-1002. Abstract
Azzalin, C. M., Reichenbach, P., Khoriauli, L., Giulotto, E., and Lingner, J. (2007). Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science 318, 798-801. Abstract
Chang, M., Arneric, M., and Lingner, J. (2007). Telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae. Genes Dev 21, 2485-2494. Abstract
Cristofari, G., Adolf, E., Reichenbach, P., Sikora, K., Terns, R. M., Terns, M. P., and Lingner, J. (2007). Human telomerase RNA accumulation in cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation. Mol Cell 27, 882-889. Abstract
Cristofari, G., Reichenbach, P., Regamey, P. O., Banfi, D., Chambon, M., Turcatti, G., and Lingner, J. (2007). Low- to high-throughput analysis of telomerase modulators with Telospot. Nat Methods 4, 851-853. Abstract
Cristofari, G., Sikora, K., and Lingner, J. (2007). Telomerase unplugged. ACS Chem Biol 2, 155-158. Abstract
De Cian, A., Cristofari, G., Reichenbach, P., De Lemos, E., Monchaud, D., Teulade-Fichou, M. P., Shin-Ya, K., Lacroix, L., Lingner, J., and Mergny, J. L. (2007). Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action. Proc Natl Acad Sci U.S.A 104, 17347-17352. Abstract
Luke, B., Azzalin, C. M., Hug, N., Deplazes, A., Peter, M., and Lingner, J. (2007). Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay. Nucleic Acids Res in press. Abstract
Redon, S., Reichenbach, P., and Lingner, J. (2007). Protein-RNA and protein-protein interactions mediate association of human EST1A/SMG6 with telomerase. Nucleic Acids Res in press.
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Azzalin, C. M., and Lingner, J. (2006). The double life of UPF1 in RNA and DNA stability pathways. Cell Cycle 5, 1496-1498. Abstract
Azzalin, C. M. , and Lingner, J. (2006). The human RNA surveillance factor UPF1 is required for S phase progression and genome stability. Curr Biol 16, 433-439. Abstract
Cristofari, G., and Lingner, J. (2006). Telomere length homeostasis requires that telomerase levels are limiting. Embo J 25, 565-574. Abstract
Cristofari, G. , and Lingner, J. (2006). The telomerase RNP. In Telomeres, T. d. Lange, V. Lundblad, and E. Blackburn, eds. (Cold Spring Harbor).
Eugster, A., Lanzuolo, C., Bonneton, M., Luciano, P., Pollice, A., Pulitzer, J. F., Stegberg, E., Berthiau, A. S., Forstemann, K., Corda, Y., Lingner, J., Geli, V., and Gilson, E. (2006). The finger subdomain of yeast telomerase cooperates with Pif1p to limit telomere elongation. Nat Struct Mol Biol 13, 734-739. Abstract
Hug, N., and Lingner, J. (2006). Telomere length homeostasis. Chromosoma 115, 413-425. Abstract
Kurth, I., Cristofari, G., and Lingner, J. (2006). An affinity oligonucleotide displacement strategy to purify ribonucleoprotein complexes applied to human telomerase. In RNA - Protein Interaction Protocols, R. J. Lin, ed. (Humana Press), in press.
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Förstemann, K. , and Lingner, J. (2005). Telomerase limits the extent of base pairing between template RNA and telomeric DNA. EMBO Rep 6, 361-366. Abstract
Kelleher, C., Kurth, I., Lingner, J. (2005). Human protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitro. Mol Cell Biol 25, 808-818. Abstract
Azzalin, C. M., Redon, S., and Lingner, J. (2005). S. Cerevisiae Est1/H. sapiens SMG6 protein family members function in telomere metabolism. In : Nonsense-mediated mRNA decay, L. E. Maquat, ed. (Landes Bioscience).
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Azzalin, CM, and Lingner, J (2004). Cell biology: telomere wedding ends in divorce. Science 304, 60-62. Abstract
Teixeira, MT, Arneric, M, Sperisen, P, and Lingner, J (2004). Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states. Cell 117, 323-335. Abstract
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Cristofari, G., and Lingner, J. (2003). Fingering the ends. How to make new telomeres. Cell 113, 552-554. Abstract
Förstemann, K., Zaug, A. J., Cech, T. R., and Lingner, J. (2003). Yeast telomerase is specialized for C/A-rich RNA templates. Nucleic Acids Res. 31, 1646-1655. Abstract
Reichenbach, P., Höss, M., Azzalin, C. M., Nabholz, M., Bucher, P., and Lingner, J. (2003). A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed. Current Biology 13, 568-574. Abstract
Szutorisz, H., Lingner, J., Cuthbert, A. P., Trott, D. A., Newbold, R. F. and Nabholz, M. (2003). A chromosome 3-encoded repressor of the human telomerase reverse transcriptase (hTERT) gene controls the state of hTERT chromatin. Cancer Res. 63, 689-695. Abstract
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Ducrest, A. L., Amacker, M., Lingner, J., and Nabholz, M. (2002). Detection of promoter activity by flow cytometric analysis of GFP reporter expression. Nucleic Acids Res 30, e65. Abstract
Ducrest, A. L., Szutorisz, H., Lingner, J., and Nabholz, M. (2002). Regulation of the human telomerase reverse transcriptase gene. Oncogene 21, 541-552. Abstract
Kelleher, C., Teixeira, M. T., Förstemann, K., and Lingner, J. (2002). Telomerase: biochemical considerations for enzyme and substrate. Trends Biochem Sci 27, 572-579. Abstract
Lingner, J., and Wenz, C. (2002). The makings of telomerases. In: Telomeres and Telomerases: Cancer and Biology, G. Krupp and R. Parwaresch, eds. (Landes Bioscience).
Pascolo, E., Wenz, C., Lingner, J., Hauel, N., Priepke, H., Kauffmann, I., Garin-Chesa, P., Rettig, W. J., Damm, K., and Schnapp, A. (2002). Mechanism of human telomerase inhibition by BIBR1532, a synthetic, non-nucleosidic drug candidate. J Biol Chem 277, 15566-15572. Abstract
Teixeira, M. T., Förstemann, K., Gasser, S. M., and Lingner, J. (2002). Intracellular trafficking of yeast telomerase components. EMBO Rep 3, 652-659. Abstract
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Damm, K., Hemmann, U., Garin-Chesa, P., Hauel, N., Kauffmann, I., Priepke, H., Niestroj, C., Daiber, C., Enenkel, B., Guillard, B., Lauritsch, I., Müller, E., Pascolo, E., Sauter, G., Pantic, M., Martens, U. M., Wenz, C., Lingner, J., Kraut, N., Rettig, W. J., and Schnapp, A. (2001). A highly selective telomerase inhibitor limiting human cancer cell proliferation. EMBO J. 20, 6958-6968. Abstract
Ducrest, A.-L., Amacker, M., Matthieu, Y., Reichenbach, P., Cuthbert, A.P., Trott, D.A., Newbold, R.F., Nabholz, M. and Lingner, J. (2001). Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity. Cancer Res. 61, 7594-7602. Abstract
Förstemann, K. and Lingner, J. (2001). Molecular basis for telomere repeat divergence in budding yeast. Mol. Cell. Biol. 21, 7277-7286. Abstract
Szutorisz, H., Palmquist, R., Roos, G., Stenling, R., Schorderet, D., Reddel, R., Lingner, J., and Nabholz, M. (2001). Rearrangements of minisatellites in the human telomerase reverse transcriptase gene are not correlated with its expression in colon carcinomas. Oncogene 20, 2600-2665. Abstract
Wenz, C., Enenkel, B., Amacker, M., Kelleher, C., Damm, K., and Lingner, J. (2001). Human telomerase contains two cooperating telomerase RNA molecules. EMBO J. 20, 3526-3534. Abstract
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Aigner, S., Lingner, J., Goodrich, K., Grosshans, C.A., Shevchenko, A., Mann, M., and Cech, T.R. (2000). Euplotes telomerase contains a La motif protein produced by apparent translational frameshifting. EMBO J. 19, 6230-6239. Abstract
Förstemann, K., Höss, M., and Lingner, J. (2000). Telomerase-dependent repeat divergence at the 3' ends of yeast telomeres. Nucleic Acids Res. 28, 2690-2694. Abstract
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Blasco, M.A., Gasser, S.M., and Lingner, J. (1999). Telomeres and telomerase, Genes Dev. 13, 2353-2359. Full text
Wu, K.-J., Grandori, C., Amacker, M., Simon-Vermot, N., Polack, A., Lingner, J., and Dalla-Favera, R. (1999). Direct activation of TERT transcription by c-MYC. Nature Genet. 21, 220-224. Abstract
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Lingner, J., and Cech, T.R. (1998). Telomerase and chromosome end maintenance. Curr. Op. Genet. Dev. 8, 226-232. Abstract
Lingner, J. (1998). Telomerase: the reverse transcriptase subunit as a key to enzymatic function and regulation during cell immortalization. Bull. Suisse Canc. 18, 38-42.
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Cech, T. R., Nakamura, T. M., and Lingner, J. (1997). Telomerase is a true reverse transcriptase. A review. Biochemistry (Mosc) 62, 1202-1205. Abstract
Cech, T. R., and Lingner, J. (1997). Telomerase and the chromosome end replication problem. Proc CIBA Found Symp 211, 20-34. Abstract
Lingner, J., Cech, T. R., Hughes, T. R., and Lundblad, V. (1997). Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity. Proc Natl Acad Sci U S A 94, 11190-11195. Full text
Lingner, J., Hughes, T. R., Shevchenko, A., Mann, M., Lundblad, V., and Cech, T. R. (1997). Reverse transcriptase motifs in the catalytic subunit of telomerase. Science 276, 561-567. Abstract
Nakamura, T. M., Morin, G. B., Chapman, K. B., Weinrich, S. L., Andrews, W. H., Lingner, J., Harley, C. B., and Cech, T. R. (1997). Telomerase catalytic subunit homologs from fission yeast and human. Science 277, 955-959. Abstract
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Lingner, J., and Cech, T. R. (1996). Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang. Proc Natl Acad Sci U S A 93, 10712-10717. Abstract
Zaug, A. J., Lingner, J., and Cech, T. R. (1996). Method for determining RNA 3' ends and application to human telomerase RNA. Nucleic Acids Res 24, 532-533. Abstract
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