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Aguet Michel
Radtke, F., Ferrero, I., Wilson, A., Lees, R., Aguet, M., and MacDonald, H.R. (2000). Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells. J. Exp. Med. 191(7), 1085-1094. Abstract
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Beard Peter
Hirt, B. (2000). Molecular biology of autonomous parvoviruses. Contrib. Microbiol. 4, 163-177. Abstract
Ogston, P., Raj, K., and Beard, P. (2000). Productive replication of adeno-associated virus can occur in human papillomavirus type 16 (HPV-16) episome-containing keratinocytes and is augmented by the HPV-16 E2 protein. J. Virol. 74, 3494-3504. Abstract
Saudan, P., Vlach, J., and Beard, P. (2000). Inhibition of S-phase progression by adeno-associated virus rep78 protein is mediated by hypophosphorylated pRb, EMBO J. 19, 4351-4361. Abstract
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Beermann Friedrich
Camacho-Hübner, A., Rossier, A., and Beermann, F. (2000). The Fugu rubripes tyrosinase gene promoter targets transgene expression to pigment cells in the mouse. Genesis 28, 99-105. Abstract
Camacho-Hübner, A., and Beermann, F. (2000). Caractéristiques cellulaires et moléculaires de la pigmentation chez les mammifères - tyrosinase et TRP. Pathol. Biol. 48, 577-583. Abstract
Gasser, S., Corthésy, P., Beermann, F., MacDonald, H., and Nabholz, M. (2000). Constitutive expression of a chimeric receptor that delivers IL-2/IL-15 signals allows antigen-independent proliferation of CD8+CD44high but not other T cells. J. Immunol. 164, 5659-5667. Abstract
Hummler, E., and Beermann, F. (2000). Scnn1 sodium channel gene family in genetically engineered mice. J. Am. Soc. Nephrol. 11, S129-S134. Abstract
Jordan, S., and Beermann, F. (2000). Nomenclature for identified pigmentation genes in the mouse. Pigment Cell Res. 13, 70-71. Abstract
Lowin-Kropf, B., Kunz, B., Beermann, F., and Held, W. (2000). Impaired natural killing of MHC class I-deficient targets by NK cells expressing a catalytically inactive form of SHP-1. J. Immunol. 165, 1314-1321. Abstract
Manga, P., Sato, K., Ye, L., Beermann, F., Lamoreux, M.L., and Orlow, S.J. (2000). Mutational analysis of the modulation of tyrosinase by tyrosinase-related proteins 1 and 2 in vitro. Pigment Cell Res. 13, 364-374. Abstract
Rachel, R.A., Murdoch, J., Beermann, F., Copp, A., and Mason, C. (2000). Retinal axon misrouting at the optic chiasm in mice with neural tube closure defects. Genesis 27, 32-47. Abstract
Thorens, B., Guillam, M., Beermann, F., Burcelin, R., and Jaquet, M. (2000). Transgenic Reexpression of GLUT1 or GLUT2 in pancreatic ß cells rescues GLUT2 null mice from early death and restores normal glucose-stimulated insulin secretion. J. Biol. Chem. 275, 23751-23758. Abstract
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Bucher Philipp
Apweiler, R., T. K. Attwood, et al. (2000). InterPro--an integrated documentation resource for protein families, domains and functional sites. Bioinformatics 16, 1145-50. Abstract
Attuil, V., Bucher, P., Rossi, M., Mutin, M., and Maryanski, J. L. (2000). Comparative T cell receptor repertoire selection by antigen after adoptive transfer: A glimpse at an antigen-specific preimmune repertoire [In Process Citation]. Proc. Natl Acad. Sci. U.S.A 97, 8473-8478. Abstract
Cavin-Périer, R., Praz, V., Junier, T., Bonnard, C., and Bucher, P. (2000). The eukaryotic promoter database (EPD). Nucleic Acids Res. 28, 302-303. Abstract
Dias Neto, E., Garcia Correa, R., Verjovski-Almeida, S., Briones, M. R., Nagai, M. A., da Silva, W., Jr., Zago, M. A., Bordin, S., Costa, F. F., Goldman, G. H., Carvalho, A. F., Matsukuma, A., Baia, G. S., Simpson, D. H., Brunstein, A., de Oliveira, P. S., Bucher, P., Jongeneel, C. V., O'Hare, M. J., Soares, F., Brentani, R. R., Reis, L. F., de Souza, S. J., and Simpson, A. J. (2000). Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. Proc. Natl Acad. Sci. U.S.A 97, 3491-3496. Abstract
Greasley, P. J., Bonnard, C., and Amati, B. (2000). Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesis. Nucleic Acids Res. 28, 446-453. Abstract
Junier, T., and Pagni, M. (2000). Dotlet: diagonal plots in a web browser. Bioinformatics 16, 178-179. Abstract
Roulet, E., Bucher, P., Schneider, R., Wingender, E., Dusserre, Y., Werner, T., and Mermod, N. (2000). Experimental analysis and computer prediction of CTF/NFI transcription factor DNA binding sites. J. Mol. Biol. 297, 833-848. Abstract
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Constam Daniel
Constam, D. B., and Robertson, E. J. (2000). SPC4/PACE4 regulates a TGFbeta signaling network during axis formation. Genes Dev. 14, 1146-1155. Abstract
Constam, D. B., and Robertson, E. J. (2000). Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping. Development 127, 245-254. Abstract
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Gönczy Pierre
Gönczy, P., Echeverri, G., Oegema, K., Coulson, A., Jones, S. J., Copley, R. R., Duperon, J., Oegema, J., Brehm, M., Cassin, E., Hannak, E., Kirkham, M., Pichler, S., Flohrs, K., Goessen, A., Leidel, S., Alleaume, A. M., Martin, C., Ozlu, N., Bork, P., and Hyman, A. A. (2000). Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 408, 331-336. Abstract
Jantsch-Plunger, V., Gönczy, P., Romano, A., Schnabel, H., Hamill, D., Schnabel, R., Hyman, A. A., and Glotzer, M. (2000). CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis. J. Cell Biol. 149, 1391-1404. Abstract
Pichler, S., Gönczy, P., Schnabel, H., Pozniakowski, A., Ashford, A., Schnabel, R., and Hyman, A. A. (2000). OOC-3, a novel putative transmembrane protein required for establishment of cortical domains and spindle orientation in the P(1) blastomere of C. elegans embryos. Development 127, 2063-2073. Abstract
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Gasser Susan
Cockell, M.M., Perrod, S., and Gasser, S.M. (2000). Analysis of Sir2p domains required for rDNA and telomeric silencing in Saccharomyces cerevisiae. Genetics 154, 1069-1083. (see "Erratum" in Genetics 155, 2021). More infoErnst, A. I., Soltermann, A., Sigrist, J. A., Widmer, L., Gasser, S. M., and Stahel, R. A. (2000). Ectopic expression of human topoisomerase IIalpha fragments and etoposide resistance in mammalian cells. Int. J. Cancer 88, 99-107. More info Frei, C., and Gasser, S.M. (2000). The yeast Sgs1 helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase specific foci. Genes & Dev. 14, 81-96. More info Frei, C., and Gasser, S.M. (2000). RecQ-like helicases: The DNA replication checkpoint connection. J. Cell Sci. 113, 2641-2646. More info Gasser, S., Corthésy, P., Beermann, F., MacDonald, H. R., and Nabholz, M. (2000). Constitutive expression of a chimeric receptor that delivers IL-2/IL-15 signals allows antigen-independent proliferation of CD8+CD44high but not other T cells. J. Immunol. 164, 5659-5667. More info Gasser, S.M. (2000). A sense of the end. Science 288, 1377-1379. More info Koering, C.E., Fourel, G., Binet-Brasselet, E., Laroche, T., Klein, F., and Gilson, E. (2000). Identification of high affinity Tbf1p-binding sites within the budding yeast genome. Nucleic Acids Res. 28, 2519-2526. More info Laroche, T., Martin, S.G., Tsai-Pflugfelder, M., and Gasser, S.M. (2000). The Dynamics of Yeast Telomeres and Silencing Proteins through the Cell Cycle. J. Struct. Biol., 129, 159-174. More info Leupin, O., Zaru, R., Laroche, T., Muller, S., and Valitutti, S. (2000). Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes. Curr. Biol. 10, 277-280. More info Pollice, A., Zibella, M.P., Bilaud, T., Laroche, T., Pulitzer, J.F., and Gilson, E. (2000). In vitro binding of nucleolin to double-stranded telomeric DNA. Biochem. Biophys. Res. Commun. 268, 909-915. More info Stone, E.M., Heun, P., Laroche, T., Pillus, L., and Gasser, S.M. (2000). MAP kinase signaling induces nuclear reorganization in budding yeast. Curr. Biol. 10, 373-382. More info
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Iggo Richard
Obata, A., Eura, M., Sasaki, J., Saya, H., Chikamatsu, K., Tada, M., Iggo, R. D., and Yumoto, E. (2000). Clinical significance of p53 functional loss in squamous cell carcinoma of the oropharynx. Int. J. Cancer (Pred. Oncol.) 89, 187-193. Abstract
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Kühn Lukas C.
Sposi, N.M., Cianetti, L.C., Tritarelli, E., Pelosi, E., Militi, S., Barberi, T., Gabbianelli, M., Saulle, E., Kühn, L.C., Peschle, C., and Testa, U. (2000). Mechanisms of differential transferrin receptor expression in normal hematopoiesis. Eur. J. Biochem. 267, 6762-6774. Abstract
Verrey, F., Meier, C., Rossier, G., and Kühn, L. C. (2000). Glycoprotein-associated amino acid exchangers: broadening the range of transport specificity. Pflugers Arch. 440, 503-512. Abstract
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Kraehenbuhl Jean-Pierre
Coste, A., Sirard, J.C., Johansen, K., Cohen, J., and Kraehenbuhl, J.P. (2000). Nasal immunization of mice with virus-like particles protects offspring against rotavirus diarrhea. J. Virol. 74, 8966-8971. More infoHathaway, L.J., and Kraehenbühl, J.P. (2000). The role of M cells in mucosal immunity. Cell. Mol. Life Sci. 57(2), 323-332. More info Hopkins, S. A., Niedergang, F., Corthésy-Theulaz, I. E., and Kraehenbuhl, J. P. (2000). A recombinant Salmonella typhimurium vaccine strain is taken up and survives within murine Peyer's patch dendritic cells. Cell Microbiol. 2, 59-68. More info Kerneis, S. Caliot, E., Stubbe, H., Bogdanova, A., Kraehenbühl, J.P., and Pringault, E. (2000). Molecular studies of the intestinal mucosal barrier physiopathology using co-cultures of epithelial and immune cells: a technical update. Microbes Infect. 2, 1119-1124. More info Kraehenbühl, J.P., and Neutra, M.R. (2000). Epithelial M cells: differentiation and function. Annu. Rev. Cell Dev. Biol. 16, 301-332. More info Kraehenbühl, J.P., and Velin, D. (2000). The airways: a site for vaccination and pathogen entry. In Mucosal immunology and ocular disease, M. Zierhut and J.V. Forrester, eds. The Netherlands: Aeolus Press, pp. 231-233. Michetti, M., Kelly, C. P., Kraehenbuhl, J. P., Bouzourene, H., and Michetti, P. (2000). Gastric mucosal alpha(4)beta(7)-integrin-positive CD4 T lymphocytes and immune protection against helicobacter infection in mice. Gastroenterology 119, 109-118. More info Niedergang, F., Sirard, J.C., Tallichet-Blanc, C., and Kraehenbühl, J.P. (2000). Entry and survival of salmonella typhimurium in dendritic cells and presentation of recombinant antigens do not require macrophage-specific virulence factors. Proc. Natl. Acad. Sci. U.S.A. 97, 14650-14655. More info Niedergang, F. and Kraehenbühl, J.P. (2000). Much ado about M cells. Trends Cell Biol. 10(4), 137-141. (Author correction in Trends Cell Biol. 10, 196). More info Schulte, R., Kerneis, S., Klinke, S., Bartels, H., Preger, S., Krahenbühl, J.P., Pringault, E., and Autenrieth, I.B. (2000). Translocation of Yersinia enterocolitica across reconstituted intestinal epithelial monolyers is triggered by Yersinia invasin binding to b1 integrins apically expressed on M-like cells. Cell. Microbiol. 2, 173-185. More info Sierro, F., Pringault, E., Simon-Assman, P., Kraehenbühl, J.P., and Debard, N. (2000). Transient expression of M-cell phenotype by enterocyte-like cells of the follicle-associated epthelium of mouse Peyer's patches. Gastroenterology 119, 734-743. More info Stubbe, H., Berdoz, J., Kraehenbühl, J.P., and Corthesy, B. (2000). Polymeric IgA is superior to monomeric IgA and IgG carrying the same variable domain in preventing Clostridium difficile toxin A damaging of T84 monolayers. J. Immunol. 164(4), 1952-1960. More info Velin, D., and Kraehenbühl, J.P. (2000). Delivery systems and adjuvants for vaccination against HIV. EXS 89, 227-237. More info
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Lingner Joachim
Aigner, S., Lingner, J., Goodrich, K., Grosshans, C.A., Shevchenko, A., Mann, M., and Cech, T.R. (2000). Euplotes telomerase contains a La motif protein produced by apparent translational frameshifting. EMBO J. 19, 6230-6239. Abstract
Förstemann, K., Höss, M., and Lingner, J. (2000). Telomerase-dependent repeat divergence at the 3' ends of yeast telomeres. Nucleic Acids Res. 28, 2690-2694. Abstract
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Mach Jean-Pierre
Buchegger, F., Allal, A. S., Roth, A., Papazyan, J. P., Dupertuis, Y., Mirimanoff, R. O., Gillet, M., Pelegrin, A., Mach, J. P., and Slosman, D. O. (2000). Combined radioimmunotherapy and radiotherapy of liver metastases from colorectal cancer: a feasibility study. Anticancer Res. 20, 1889-1896. More infoBuchegger, F., Roth, A., Allal, A., Dupertuis, Y. M., Slosman, D. O., Delaloye, A. B., and Mach, J. P. (2000). Radioimmunotherapy of colorectal cancer liver metastases: combination with radiotherapy. Ann. N.Y. Acad. Sci. 910, 263-269; discussion 269-270. More info Cloutier, S. M., S. Couty, et al. (2000). Streptabody, a high avidity molecule made by tetramerization of in vivo biotinylated, phage display-selected scFv fragments on streptavidin. Mol Immunol. 37, 1067-77. More info Gervaz, P., Blanchard, A., Pampallona, S., Mach, J. P., Fontolliet, C., and Gillet, M. (2000). Prognostic value of postoperative carcinoembryonic antigen concentration and extent of invasion of resection margins after hepatic resection for colorectal metastases. Eur. J. Surg. 166, 557-561. More info Pèlegrin, A., F. Xavier, et al. (2000). [Immunotargeting of tumors: state of the art and prospects in 2000]. Bull Cancer 87(11): 777-91. More info Robert, B., Guillaume, P., Luescher, I., Romero, P., and Mach, J.P. (2000). Antibody-conjugated MHC class I tetramers can target tumor cells for specific lysis by T lymphocytes. Eur. J. Immunol. 30, 3165-3170. More info Vuagnat, B.B., Mach, J., and Le Doussal, J. (2000). Activation of the alternative pathway of human complement by autologous cells expressing transmembrane recombinant properdin. Mol. Immunol. 37, 467-478. More info
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Mirkovitch Jovan
Fivaz, J., Bassi, M. C., Pinaud, S., and Mirkovitch, J. (2000). RNA polymerase II promoter-proximal pausing upregulates c-fos gene expression. Gene 255, 185-194. More infoFivaz, J., Bassi, M. C., Pinaud, S., Richman, L., Price, M., and Mirkovitch, J. (2000). EBV-derived episomes to probe chromatin structure and gene expression in human cells. Methods Mol. Biol. 133, 167-182. More info Fivaz, J., Bassi, M. C., Price, M., Pinaud, S., and Mirkovitch, J. (2000). Precisely positioned nucleosomes are not essential for c-fos regulation in vivo. Gene 255, 169-184. More info Souici, A. C., Mirkovitch, J., Hausel, P., Keefer, L. K., and Felley-Bosco, E. (2000). Transition mutation in codon 248 of the p53 tumor suppressor gene induced by reactive oxygen species and a nitric oxide-releasing compound. Carcinogenesis 21, 281-287. More info
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Peter Matthias
Bähler, J., and Peter, M. (2000). Cell polarity in yeast. In: Cell Polarity, D. G. Drubin ed. (Oxford University Press), pp. 21-77. Blondel, M., Galan, J.M., and Peter, M. (2000). Isolation and characterization of HRT1 using a genetic screen for mutants unable to degrade Gic2p in Saccharomyces cerevisiae, Genetics 155, 1033-1044. More info Blondel, M., Galan, J. M., Chi, Y., Lafourcade, C., Longaretti, C., Deshaies, R. J., and Peter, M. (2000). Nuclear-specific degradation of far1 is controlled by the localization of the F-box protein cdc4. EMBO J. 19, 6085-6097. More info Gulli, M., Jaquenoud, M., Shimada, Y., Niederhauser, G., Wiget, P., and Peter, M. (2000). Phosphorylation of the cdc42 exchange factor cdc24 by the PAK-like kinase cla4 may regulate polarized growth in yeast. Mol. Cell 6, 1155-1167. More info Jaquenoud, M., and Peter, M. (2000). Gic2p may link activated Cdc42p to components involved in actin polarisation including Bni1p and Aip3p/Bud6p, Mol. Cell Biol. 20, 6244-6258. More info Shimada, Y., Gulli, M.-P., and Peter, M. (2000). Nuclear sequestration of the exchange factor Cdc24 by Far1 regulates cell polarity during yeast mating. Nature Cell Biol. 2, 117-124. More info Van Drogen, F., O'Rourke, S.M., Stucke, V.M., Jaquenoud, M., Neiman, A.M., and Peter, M. (2000). Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signaling in vivo. Curr. Biol. 10, 630-639. More info Wirbelauer, C., Sutterluty, H., Blondel, M., Gstaiger, M., Peter, M., Reymond, F., and Krek, W. (2000). The F-box protein skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of cul1 in the suppression of skp2 expression in quiescent fibroblasts. EMBO J. 19, 5362-5375. More info
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Radtke Freddy
Wilson, A., Ferrero, I., MacDonald, H. R., and Radtke, F. (2000). Cutting edge: an essential role for Notch-1 in the development of both thymus-independent and -dependent T cells in the gut. J Immunol 165, 5397-5400. Abstract
Radtke, F., Ferrero, I., Wilson, A., Lees, R., Aguet, M., and MacDonald, H. R. (2000). Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells. J Exp Med 191, 1085-1094. Abstract
Leimeister, C., Dale, K., Fischer, A., Klamt, B., Hrabe de Angelis, M., Radtke, F., McGrew, M. J., Pourquie, O., and Gessler, M. (2000). Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors. Dev Biol 227, 91-103. Abstract
Di Santo, J. P., Radtke, F., and Rodewald, H. R. (2000). To be or not to be a pro-T? Curr Opin Immunol 12, 159-165. Abstract
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Reichmann Ernst
Schröter, M., Peli, J., Hahne, M., Tschopp, J., and Reichmann, E. (2000). Fas-dependent tissue turnover is implicated in tumor cell clearance. Oncogene 19, 1794-1800. More info
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Simanis Viesturs
Cerutti, L., and Simanis, V. (2000). Controlling the end of the cell cycle. Curr. Opin. Genet. Dev. 10, 65-69. Abstract
Le Goff, X., Motegi, F., Salimova, E., Mabuchi, I., and Simanis, V. (2000). The S. pombe rlc1 gene encodes a putative myosin regulatory light chain that binds the type II myosins myo3p and myo2p. J. Cell Sci. 113, 4157-4163. Abstract
Salimova, E., Sohrmann, M., Fournier, N., and Simanis, V. (2000). The S. pombe orthologue of the S. cerevisiae mob1 gene is essential and functions in signalling the onset of septum formation. J. Cell Sci. 113, 1695-1704. Abstract
Samuel, J. M., Fournier, N., Simanis, V., and Millar, J. B. (2000). spo12 is a multicopy suppressor of mcs3 that is periodically expressed in fission yeast mitosis . Mol. Gen. Genet. 264, 306-316. Abstract
Utzig, S., Fankhauser, C., and Simanis, V. (2000). Periodic Accumulation of cdc15 mRNA is not Necessary for Septation in Schizosaccharomyces pombe. J. Mol. Biol. 302, 751-759. Abstract
Zilahi, E., Salimova, E., Simanis, V., and Sipiczki, M. (2000). The S. pombe sep1 gene encodes a nuclear protein that is required for periodic expression of the cdc15 gene. FEBS Lett. 481, 105-108. Abstract
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Sordat Bernard
Keller, H.U., Hunziker, I.P., Sordat, B., Niggli, V., and Sroka, J. (2000). Protein kinase C isoforms involved in regulation of cell shape and locomotion of human fibrosarcoma HT1080 cells. Int. J. Cancer 88, 195-203. More infoLahm, H., Hoeflich, A., Andre, S., Sordat, B., Kaltner, H., Wolf, E., and Gabius, H. (2000). Gene expression of galectin-9/ecalectin, a potent eosinophil chemoattractant, and/or the insertional isoform in human colorectal carcinoma cell lines and detection of frame-shift mutations for protein sequence truncations in the second functional lectin domain . Int. J. Oncol. 17, 519-524. More info Schneider, M.R., Hoeflich, A., Fischer, J.R., Wolf, E., Sordat, B., and Lahm, H. (2000). Interleukin-6 stimulates clonogenic growth of primary and metastatic human colon carcinoma cells. Cancer Lett. 151, 31-38. More info Sordat, I., Rousselle, P., Chaubert, P., Petermann, O., Aberdam, D., Bosman, F.T., and Sordat, B. (2000). Tumor cell budding and laminin-5 expression in colorectal carcinoma can be modulated by the tissue micro-environment. Int. J. Cancer 88, 708-717. More info
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Trumpp Andreas
Buchholz, F., Refaeli, Y., Trumpp, A., and Bishop, J.M. (2000). Inducible chromosomal translocation of AML and ETO genes through Cre/loxP mediated recombination in the mouse. EMBO Reports 1, 133-139. Abstract
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