|
|
Amsen, D., Antov, A., Jankovic, D., Sher, A., Radtke, F., Souabni, A., Busslinger, M., McCright, B., Gridley, T., and Flavell, R. A. (2007). Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 27, 89-99. Abstract
Besseyrias, V., Fiorini, E., Strobl, L. J., Zimber-Strobl, U., Dumortier, A., Koch, U., Arcangeli, M. L., Ezine, S., Macdonald, H. R., and Radtke, F. (2007). Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation. J Exp Med 204, 331-343. Abstract
Kelly, A. P., Finlay, D. K., Hinton, H. J., Clarke, R. G., Fiorini, E., Radtke, F., and Cantrell, D. A. (2007). Notch-induced T cell development requires phosphoinositide-dependent kinase 1. Embo J 26, 3441-3450. Abstract
Koch, U., and Radtke, F. (2007). Haematopoietic stem cell niche in Drosophila. Bioessays 29, 713-716. Abstract
Koch, U., and Radtke, F. (2007). Notch and cancer: a double-edged sword. Cell Mol Life Sci in press. Abstract
Koch, U., Wilson, A., Cobas, M., Kemler, R., Macdonald, H. R., and Radtke, F. (2007). Simultaneous loss of {beta}- and {gamma}-catenin does not perturb hematopoiesis or lymphopoiesis. Blood in press. Abstract
Komine, O., Nagaoka, M., Watase, K., Gutmann, D. H., Tanigaki, K., Honjo, T., Radtke, F., Saito, T., Chiba, S., and Tanaka, K. (2007). The monolayer formation of Bergmann glial cells is regulated by Notch/RBP-J signaling. Dev Biol 311, 238-250. Abstract
Santos, M. A., Sarmento, L. M., Rebelo, M., Doce, A. A., Maillard, I., Dumortier, A., Neves, H., Radtke, F., Pear, W. S., Parreira, L., and Demengeot, J. (2007). Notch1 engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells. Proc Natl Acad Sci U S A 104, 15454-15459. Abstract
Schouwey, K., Delmas, V., Larue, L., Zimber-Strobl, U., Strobl, L. J., Radtke, F., and Beermann, F. (2007). Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner. Dev Dyn 236, 282-289. Abstract
Takeshita, K., Satoh, M., Ii, M., Silver, M., Limbourg, F. P., Mukai, Y., Rikitake, Y., Radtke, F., Gridley, T., Losordo, D. W., and Liao, J. K. (2007). Critical role of endothelial Notch1 signaling in postnatal angiogenesis. Circ Res 100, 70-78. Abstract
Vauclair, S., Majo, F., Durham, A. D., Ghyselinck, N. B., Barrandon, Y., and Radtke, F. (2007). Corneal epithelial cell fate is maintained during repair by Notch1 signaling via the regulation of vitamin A metabolism. Dev Cell 13, 242-253. Abstract
 |
Nemir, M., Croquelois, A., Pedrazzini, T., and Radtke, F. (2006). Induction of cardiogenesis in embryonic stem cells via downregulation of Notch1 signaling. Circ Res 98, 1471-1478. Abstract
Radtke, F., Clevers, H., and Riccio, O. (2006). From gut homeostasis to cancer. Curr Mol Med 6, 275-289. Abstract
Wang, X. D., Leow, C. C., Zha, J., Tang, Z., Modrusan, Z., Radtke, F., Aguet, M., de Sauvage, F. J. , and Gao, W. Q. (2006). Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation. Dev Biol 290, 66-80. Abstract
Wilson, A., and Radtke, F. (2006). Multiple functions of Notch signaling in self-renewing organs and cancer. FEBS Lett 580, 2860-2868. Abstract
|
Croquelois, A., Blindenbacher, A., Terracciano, L., Wang, X., Langer, I., Radtke, F. , and Heim, M. H. (2005). Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice. Hepatology 41, 487-496. Abstract
Dumortier, A., Wilson, A., MacDonald, H. R. , and Radtke, F. (2005). Paradigms of notch signaling in mammals. Int J Hematol 82, 277-284. Abstract
Francis, J. C., Radtke, F. , and Logan, M. P. (2005). Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud. Dev Dyn 234, 1006-1015. Abstract
Limbourg, F. P., Takeshita, K., Radtke, F., Bronson, R. T., Chin, M. T. , and Liao, J. K. (2005). Essential role of endothelial Notch1 in angiogenesis. Circulation 111, 1826-1832. Abstract
Mancini, S. J., Mantei, N., Dumortier, A., Suter, U., Macdonald, H. R. , and Radtke, F. (2005). Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. Blood 105, 2340-2342. Abstract
Radtke, F. , and Clevers, H. (2005). Self-renewal and cancer of the gut: two sides of a coin. Science 307, 1904-1909. Abstract
Radtke, F., Schweisguth, F. , and Pear, W. (2005). The Notch 'gospel'. EMBO Rep 6, 1120-1125. Abstract
Radtke, F., Wilson, A. , and MacDonald, H. R. (2005). Notch signaling in hematopoiesis and lymphopoiesis: lessons from Drosophila. Bioessays 27, 1117-1128. Abstract
van Es, J. H., van Gijn, M. E., Riccio, O., van den Born, M., Vooijs, M., Begthel, H., Cozijnsen, M., Robine, S., Winton, D. J., Radtke, F. , and Clevers, H. (2005). Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435, 959-963. Abstract
Vauclair, S., Nicolas, M., Barrandon, Y. , and Radtke, F. (2005). Notch1 is essential for postnatal hair follicle development and homeostasis. Dev Biol 284, 184-193. Abstract
Nyfeler, Y., Kirch, R. D., Mantei, N., Leone, D. P., Radtke, F., Suter, U., and Taylor, V. (2005). Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal. Embo J 24, 3504-3515. Abstract
|
Yoon, K., Nery, S., Rutlin, M. L., Radtke, F., Fishell, G., and Gaiano, N. (2004). Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors. J Neurosci 24, 9497-9506. Abstract
Tacchini-Cottier, F., Allenbach, C., Otten, L. A., and Radtke, F. (2004). Notch1 expression on T cells is not required for CD4+ T helper differentiation. Eur J Immunol 34, 1588-1596. Abstract
Radtke, F., Wilson, A., Mancini, S. J., and MacDonald, H. R. (2004). Notch regulation of lymphocyte development and function. Nat Immunol 5, 247-253. Abstract
Radtke, F., Wilson, A., and MacDonald, H. R. (2004). Notch signaling in T- and B-cell development. Curr Opin Immunol 16, 174-179. Abstract
Hoflinger, S., Kesavan, K., Fuxa, M., Hutter, C., Heavey, B., Radtke, F., and Busslinger, M. (2004). Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors. J Immunol 173, 3935-3944. Abstract
Cobas, M., Wilson, A., Ernst, B., Mancini, S. J., MacDonald, H. R., Kemler, R., and Radtke, F. (2004). Beta-catenin is dispensable for hematopoiesis and lymphopoiesis. J Exp Med 199, 221-229. Abstract
|
Radtke, F., and Raj, K. (2003). The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat Rev Cancer 3, 756-767. Abstract
Pear, W. S., and Radtke, F. (2003). Notch signaling in lymphopoiesis. Semin Immunol 15, 69-79. Abstract
Nicolas, M., Wolfer, A., Raj, K., Kummer, J. A., Mill, P., van Noort, M., Hui, C. C., Clevers, H., Dotto, G. P., and Radtke, F. (2003). Notch1 functions as a tumor suppressor in mouse skin. Nat Genet 33, 416-421. Abstract
|
Wolfer, A., Wilson, A., Nemir, M., MacDonald, H. R., and Radtke, F. (2002). Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes. Immunity 16, 869-879. Abstract
Radtke, F., Wilson, A., Ernst, B., and MacDonald, H. R. (2002). The role of Notch signaling during hematopoietic lineage commitment. Immunol Rev 187, 65-74. Abstract
Lutolf, S., Radtke, F., Aguet, M., Suter, U., and Taylor, V. (2002). Notch1 is required for neuronal and glial differentiation in the cerebellum. Development 129, 373-385. Abstract
Genoud, S., Lappe-Siefke, C., Goebbels, S., Radtke, F., Aguet, M., Scherer, S. S., Suter, U., Nave, K. A., and Mantei, N. (2002). Notch1 control of oligodendrocyte differentiation in the spinal cord. J Cell Biol 158, 709-718. Abstract
Ferrero, I., Held, W., Wilson, A., Tacchini-Cottier, F., Radtke, F., and MacDonald, H. R. (2002). Mouse CD11c(+) B220(+) Gr1(+) plasmacytoid dendritic cells develop independently of the T-cell lineage. Blood 100, 2852-2857. Abstract
|
Wolfer, A., Bakker, T., Wilson, A., Nicolas, M., Ioannidis, V., Littman, D. R., Lee, P. P., Wilson, C. B., Held, W., MacDonald, H. R., and Radtke, F. (2001). Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. Nat Immunol 2, 235-241. Abstract
Wilson, A., MacDonald, H. R., and Radtke, F. (2001). Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus. J Exp Med 194, 1003-1012. Abstract
Rangarajan, A., Talora, C., Okuyama, R., Nicolas, M., Mammucari, C., Oh, H., Aster, J. C., Krishna, S., Metzger, D., Chambon, P., Miele, L., Aguet, M., Radtke, F., and Dotto, G. P. (2001). Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. Embo J 20, 3427-3436. Abstract
MacDonald, H. R., Radtke, F., and Wilson, A. (2001). T cell fate specification and alphabeta/gammadelta lineage commitment. Curr Opin Immunol 13, 219-224. Abstract
MacDonald, H. R., Wilson, A., and Radtke, F. (2001). Notch1 and T-cell development: insights from conditional knockout mice. Trends Immunol 22, 155-160. Abstract
|
Wilson, A., Ferrero, I., MacDonald, H. R., and Radtke, F. (2000). Cutting edge: an essential role for Notch-1 in the development of both thymus-independent and -dependent T cells in the gut. J Immunol 165, 5397-5400. Abstract
Radtke, F., Ferrero, I., Wilson, A., Lees, R., Aguet, M., and MacDonald, H. R. (2000). Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells. J Exp Med 191, 1085-1094. Abstract
Leimeister, C., Dale, K., Fischer, A., Klamt, B., Hrabe de Angelis, M., Radtke, F., McGrew, M. J., Pourquie, O., and Gessler, M. (2000). Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors. Dev Biol 227, 91-103. Abstract
Di Santo, J. P., Radtke, F., and Rodewald, H. R. (2000). To be or not to be a pro-T? Curr Opin Immunol 12, 159-165. Abstract
|
Radtke, F., Wilson, A., Stark, G., Bauer, M., van Meerwijk, J., MacDonald, H. R., and Aguet, M. (1999). Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 10, 547-558. Abstract
Gerber, H. P., Hillan, K. J., Ryan, A. M., Kowalski, J., Keller, G. A., Rangell, L., Wright, B. D., Radtke, F., Aguet, M., and Ferrara, N. (1999). VEGF is required for growth and survival in neonatal mice. Development 126, 1149-1159. Abstract
|
|
