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Appay, V., Bosio, A., Lokan, S., Wiencek, Y., Biervert, C., Kusters, D., Devevre, E., Speiser, D., Romero, P., Rufer, N., and Leyvraz, S. (2007). Sensitive Gene Expression Profiling of Human T Cell Subsets Reveals Parallel Post-Thymic Differentiation for CD4+ and CD8+ Lineages. J Immunol 179, 7406-7414. Abstract
Appay, V., Voelter, V., Rufer, N., Reynard, S., Jandus, C., Gasparini, D., Lienard, D., Speiser, D. E., Schneider, P., Cerottini, J. C., Romero, P., and Leyvraz, S. (2007). Combination of transient lymphodepletion with busulfan and fludarabine and peptide vaccination in a phase I clinical trial for patients with advanced melanoma. J Immunother 30, 240-250. Abstract
Barbey, C., Baumgaertner, P., Devevre, E., Rubio-Godoy, V., Derre, L., Bricard, G., Guillaume, P., Luescher, I. F., Lienard, D., Cerottini, J. C., Romero, P., Rufer, N., and Speiser, D. E. (2007). IL-12 Controls Cytotoxicity of a Novel Subset of Self-Antigen-Specific Human CD28+ Cytolytic T Cells. J Immunol 178, 3566-3574. Abstract
Derre, L., Bruyninx, M., Baumgaertner, P., Devevre, E., Corthesy, P., Touvrey, C., Mahnke, Y. D., Pircher, H., Voelter, V., Romero, P., Speiser, D. E., and Rufer, N. (2007). In Vivo Persistence of Codominant Human CD8+ T Cell Clonotypes Is Not Limited by Replicative Senescence or Functional Alteration. J Immunol 179, 2368-2379. Abstract
Jorritsma, A., Gomez-Eerland, R., Dokter, M., van de Kasteele, W., Zoet, Y. M., Doxiadis, II, Rufer, N., Romero, P., Morgan, R. A., Schumacher, T. N., and Haanen, J. B. (2007). Selecting highly affine and well-expressed TCRs for gene therapy of melanoma. Blood 110, 3564-3572. Abstract
Romero, P., Zippelius, A., Kurth, I., Pittet, M. J., Touvrey, C., Iancu, E. M., Corthesy, P., Devevre, E., Speiser, D. E., and Rufer, N. (2007). Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes. J Immunol 178, 4112-4119. Abstract
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Appay, V., Jandus, C., Voelter, V., Reynard, S., Coupland, S. E., Rimoldi, D., Lienard, D., Guillaume, P., Krieg, A. M., Cerottini, J. C., Romero, P., Leyvraz, S., Rufer, N., and Speiser, D. E. (2006). New Generation Vaccine Induces Effective Melanoma-Specific CD8+ T Cells in the Circulation but Not in the Tumor Site. J Immunol 177, 1670-1678. Abstract
Appay, V., Speiser, D. E., Rufer, N., Reynard, S., Barbey, C., Cerottini, J. C., Leyvraz, S., Pinilla, C., and Romero, P. (2006). Decreased specific CD8(+) T cell cross-reactivity of antigen recognition following vaccination with Melan-A peptide. Eur J Immunol 36, 1805-1814. Abstract
Baumgaertner, P., Rufer, N., Devevre, E., Derre, L., Rimoldi, D., Geldhof, C., Voelter, V., Lienard, D., Romero, P. , and Speiser, D. E. (2006). Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens. Cancer Res 66, 1912-1916. Abstract
Bianchi, T., Rufer, N., Macdonald, H. R. , and Migliaccio, M. (2006). The tumor suppressor p16(Ink4a) regulates T lymphocyte survival. Oncogene 25, 4110-4115. Abstract
Colombetti, S., Fagerberg, T., Baumgartner, P., Chapatte, L., Speiser, D. E., Rufer, N., Michielin, O., and Levy, F. (2006). Impact of orthologous melan-A peptide immunizations on the anti-self melan-A/HLA-A2 T cell cross-reactivity. J Immunol 176, 6560-6567. Abstract
Menzel, O., Migliaccio, M., Goldstein, D. R., Dahoun, S., Delorenzi, M., and Rufer, N. (2006). Mechanisms regulating the proliferative potential of human CD8+ T lymphocytes overexpressing telomerase. J Immunol 177, 3657-3668. Abstract
Migliaccio, M., Alves, P. M., Romero, P. , and Rufer, N. (2006). Distinct mechanisms control human naive and antigen-experienced CD8+ T lymphocyte proliferation. J Immunol 176, 2173-2182. Abstract
Speiser, D. E., Baumgaertner, P., Barbey, C., Rubio-Godoy, V., Moulin, A., Corthesy, P., Devevre, E., Dietrich, P. Y., Rimoldi, D., Lienard, D., Cerottini, J. C., Romero, P., and Rufer, N. (2006). A novel approach to characterize clonality and differentiation of human melanoma-specific T cell responses: spontaneous priming and efficient boosting by vaccination. J Immunol 177, 1338-1348. Abstract
Tabiasco, J., Devevre, E., Rufer, N., Salaun, B., Cerottini, J. C., Speiser, D., and Romero, P. (2006). Human effector CD8+ T lymphocytes express TLR3 as a functional coreceptor. J Immunol 177, 8708-8713. Abstract
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Migliaccio, M., Raj, K., Menzel, O. , and Rufer, N. (2005). Mechanisms that limit the in vitro proliferative potential of human CD8+ T lymphocytes. J Immunol 174, 3335-3343. Abstract
Montes, M., Rufer, N., Appay, V., Reynard, S., Pittet, M. J., Speiser, D. E., Guillaume, P., Cerottini, J. C., Romero, P. , and Leyvraz, S. (2005). Optimum in vitro expansion of human antigen-specific CD8 T cells for adoptive transfer therapy. Clin Exp Immunol 142, 292-302. Abstract
Rufer, N. (2005). Molecular tracking of antigen-specific T-cell clones during immune responses. Curr Opin Immunol 17, 441-447. Abstract
Rufer, N, Reichenbach, P, Romero, P (2005). Methods for the Ex Vivo Characterization of Human CD8+ T Subsets Based on Gene Expression and Replicative History Analysis. Methods Mol Med 109, 265-284. Abstract
Speiser, D. E., Lienard, D., Rufer, N., Rubio-Godoy, V., Rimoldi, D., Lejeune, F., Krieg, A. M., Cerottini, J. C. , and Romero, P. (2005). Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. J Clin Invest 115, 739-746. Abstract
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Papagno, L, Spina, CA, Marchant, A, Salio, M, Rufer, N, Little, S, Dong, T, Chesney, G, Waters, A, Easterbrook, P, Dunbar, PR, Shepherd, D, Cerundolo, V, Emery, V, Griffiths, P, Conlon, C, McMichael, AJ, Richman, DD, Rowland-Jones, SL, and Appay, V (2004). Immune activation and CD8(+) T-cell differentiation towards senescence in HIV-1 infection. PLoS Biol 2, E20. Abstract
Vuadens, F, Rufer, N, Kress, A, Corthesy, P, Schneider, P, and Tissot, JD (2004). Identification of swiprosin 1 in human lymphocytes. Proteomics 4, 2216-2220. Abstract
Zippelius, A., Bioley, G., Le Gal, F. A., Rufer, N., Brandes, M., Batard, P., De Smedt, M., Plum, J., Speiser, D. E., Cerottini, J. C., et al. (2004). Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues. J Immunol 172, 2773-2777. Abstract
Zippelius, A, Batard, P, Rubio-Godoy, V, Bioley, G, Lienard, D, Lejeune, F, Rimoldi, D, Guillaume, P, Meidenbauer, N, Mackensen, A, Rufer, N, Lubenow, N, Speiser, D, Cerottini, JC, Romero, P, and Pittet, MJ (2004). Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer Res 64, 2865-2873. Abstract
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Bigouret, V., Hoffmann, T., Arlettaz, L., Villard, J., Colonna, M., Ticheli, A., Gratwohl, A., Samii, K., Chapuis, B., Rufer, N., and Roosnek, E. (2003). Monoclonal T-cell expansions in asymptomatic individuals and in patients with large granular leukemia consist of cytotoxic effector T cells expressing the activating CD94:NKG2C/E and NKD2D killer cell receptors. Blood 101, 3198-3204. Abstract
Rufer, N. and M. Nabholz (2003). [Telomerase, elixir of life for human cells?]. Med Sci (Paris) 19, 345-350. Abstract
Rufer, N., Zippelius, A., Batard, P., Pittet, M. J., Kurth, I., Corthésy, P., Cerottini, J. C., Leyvraz, S., Roosnek, E., Nabholz, M., and Romero, P. (2003). Ex-vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions. Blood 102, 1779-1787. Abstract
Sauce, D., Rufer, N., Mercier, P., Bodinier, M., Rémy-Martin, J. P., Duperrier, A., Ferrand, C., Herve, P., Romero, P., Lang, F., Tiberghien, P. and Robinet, E. (2003). Retrovirus-mediated gene transfer in polyclonal T cells results in lower apoptosis and enhanced ex vivo cell expansion of CMV-reactive CD8 T cells as compared to EBV-reactive CD8 T cells. Blood 102, 1241-1248. Abstract
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Einsele, H., Roosnek, E., Rufer, N., Sinzger, C., Riegler, S., Loffler, J., Grigoleit, U., Moris, A., Rammensee, H. G., Kanz, L., et al. (2002). Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy. Blood 99, 3916-3922. Abstract
Kwak, B. R., Myit, S., Mulhaupt, F., Veillard, N., Rufer, N., Roosnek, E., and Mach, F. (2002). PPARgamma but not PPARalpha ligands are potent repressors of major histocompatibility complex class II induction in atheroma-associated cells. Circ Res 90, 356-362. Abstract
Romero, P., Valmori, D., Pittet, M. J., Zippelius, A., Rimoldi, D., Lévy, F., Dutoit, V., Ayyoub, M., Rubio-Godoy, V., Michielin, O., Guillaume, P., Batard, P., Luescher, I.F., Lejeune, F., Lienard, D., Rufer, N., Dietrich, P.Y., Speiser, D.E. and Cerottini, J.-C.(2002). Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma. Immunol Rev 188, 81-96. Abstract
Zippelius, A., Pittet, M. J., Batard, P., Rufer, N., de Smedt, M., Guillaume, P., Ellefsen, K., Valmori, D., Lienard, D., Plum, J., et al. (2002). Thymic selection generates a large T cell pool recognizing a self-peptide in humans. J Exp Med 195, 485-494. Abstract
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