Congratulations to Efe Erdes, who is supported by the ISREC Foundation, on his publication in "Frontiers in Immunology". The article describes the impact of increasing NY-ESO-1 tumor antigen affinity of T-cell receptors (TCRs) on the activation of T lymphocytes and their signaling cascade, as well as on their regulation at the level of the SHP phosphatase molecules. Efe Erdes is first co-author of this paper, along with Danilo Presotto, initiator of the study.


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