Pediatric Leukemia – Prof. Camilla Jandus (UNIGE), Dr Francesco Ceppi and Prof. George Coukos (CHUV)

Date de publication


TCR-engineered CD4 T cell transfer for optimized cancer immunotherapy in adult and pediatric patients

This is a highly translational project aiming at harnessing the tumoricidal activities of CD4+ T cells to optimize cancer immunotherapies. The project includes preclinical validation of TCR-engineered CD4 T cells and the setup of a Phase 1 clinical trial for relapsed and refractory solid tumors in both adult and childhood cohorts.