Pediatric Leukemia – Prof. Camilla Jandus (UNIGE), Dr Francesco Ceppi and Prof. George Coukos (CHUV)
Project of Prof. Camilla Jandus, University of Geneva, and Dr. Francesco Ceppi and Prof. George Coukos, Centre Hospitalier Universitaire Vaudois.
This is a highly translational project aiming at harnessing the tumoricidal activities of CD4+ T cells to optimize cancer immunotherapies. The project includes preclinical validation of TCR-engineered CD4 T cells and the setup of a Phase 1 clinical trial for relapsed and refractory solid tumors in both adult and childhood cohorts.