In this interview, Prof. Mikaël Pittet (UNIGE/HUG), immunologist and holder of the ISREC Foundation Immuno-Oncology Chair, reviews scientific observations on the effects of a ketogenic diet on the behavior of CAR-T cells programmed to recognize and attack tumor cells.
Interview (in French): Le régime cétogène et ses capacités à lutter contre certaines maladies – rts.ch – Portail Audio
The ISREC Foundation is proud to have contributed to the research of Prof. Johanna Joyce and her team. They have published a detailed new cellular map of the tumor microenvironment in the prestigious journal Immunity. These invaluable findings advance our understanding of the cellular interactions within tumors and pave the way for novel therapeutic approaches.
Link to the article Single-cell atlas of endothelial and mural cells across primary and metastatic brain tumors: Immunity
Congratulations to Prof. Douglas Hanahan. The emeritus scientist of the Lausanne branch of Ludwig Cancer Research and emeritus professor at EPFL’s Swiss Institute for Experimental Cancer Research (ISREC) has won the prestigious Pezcoller-AACR award for his groundbreaking contributions to cancer biology; a well-deserved recognition for a scientist whose work has profoundly influenced cancer research.
Every donation counts 🎗, and every donor makes a real difference.
Once a year, World Cancer Day offers the opportunity to raise awareness of this disease around the world.
Thanks to your generosity, the ISREC Foundation can turn all contributions into a direct and tangible impact in the fight against cancer. We support innovative, life-changing research projects. 🌍 Cancer must be fought globally, but together, we can effectively tackle this disease at a local level. Every donation creates change.
Join us at our public conference on February 5th to find out how your donation impacts research and patients.
For more information click here
To mark the 60th anniversary of the ISREC Foundation, don’t miss our public lecture on Wednesday 5 February 2025, to be held at AGORA from 6pm, with the participation of Prof. Curzio Rüegg.
Congratulations to Prof. Johanna Joyce, Prof. George Coukos, Prof. Raphael Gottardo, Prof. Olivier Michielin and Prof. Mikaël Pittet: according to the prestigious list published by Clarivate, they are among the most frequently cited scientists in 2024.
This distinction reflects the remarkable impact of their work, ranking in the top 1% of the most cited publications worldwide. It testifies to the important role of their research in the advancement of science and encourages new interdisciplinary collaborations.
We wish to express our gratitude to Syslog Informatique SA, a company that is celebrating its 40th anniversary this year. Syslog is a long-standing partner of the ISREC Foundation that has been supporting us in the field of IT accounting for over 25 years.
To mark its 40th anniversary, the company has decided to make a donation to the ISREC Foundation, symbolizing its ongoing commitment to our cause. Many thanks to Sandro Arcioni and the entire Syslog team for their trust and support.
Link to the article (In French)
Congratulations are in order for Prof. George Coukos, director of the oncology department at UNIL-CHUV, and director of the Ludwig Institute for Cancer Research, Lausanne Branch: he has been elected as a member of the National Academy of Medicine (NAM).
This honor recognizes his groundbreaking contributions to oncology and immunotherapy. His research on the correlation between T cell infiltration and favorable prognosis in ovarian cancer has paved the way for new treatments for solid tumors. A well-deserved tribute to a career dedicated to innovation in oncology.
For more information: National Academy of Medicine Elects 100 New Members – National Academy of Medicine
Congratulations to Prof. Denis Migliorini, M.D., holder of the ISREC Foundation chair in brain tumor immunology: he and his colleagues at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have achieved a significant breakthrough in the treatment of glioblastoma, the most common and aggressive form of brain cancer.
Prof. Migliorini’s team has succeeded in identifying a specific marker on the surface of tumor cells and in generating CAR-T immune cells capable of targeting and killing diseased cells while sparing healthy tissues. These promising results, published in the journal Cancer Immunology Research, are a first step towards the development of clinical trials aimed at improving treatments for this devastating disease.
For more information: https://www.unige.ch/medias/en/2024/des-cellules-programmees-pour-cibler-les-tumeurs-cerebrales
Congratulations to Prof. Hall, a scientist at the Biozentrum of the University of Basel and a member of our Foundation Council as well as the President of our Scientific Board. He has received this prestigious award in recognition of his groundbreaking contributions to our understanding of the molecular mechanisms that regulate cell growth and ageing.
Michael Hall has discovered two proteins, “Gene Target of Rapamycin 1 and 2”, also known as TOR1 and TOR2, that regulate cell growth and metabolism in response to nutrients. These proteins play a central role in the ageing process and the development of age-related diseases such as cancer, diabetes and cardiovascular diseases.
These discoveries have paved the way for an important area of research that has since developed considerably.
For more information: Michael N. Hall – 2024 Balzan Prize for Biological Mechanisms of Ageing
